Tom Gridley, PhD
Faculty Scientist
Thomas.Gridley@mainehealth.org
Research Interests
- Genetic pathways in mammalian embryonic development and their role in human disease
- Linking gene mutations to human disease
Dr. Gridley is a geneticist with more than thirty years of experience studying genes and pathways important for embryonic development in mammals, and the connections between mutations in these genes and congenital and acquired human disease. At MaineHealth, Dr. Gridley formerly was Director of the Center for Molecular Medicine and Vice Chair of the MaineHealth Institutional Review Board. He currently works in the Administrative Cores for the Northern New England Clinical and Translational Research Network and the COBRE in Acute Care Research and Rural Health.
A complete list of publications can be found on My NCBI
Mouse Models of Development and Disease, Volume 148: Current Topics in Developmental Biology. (2022) T. Gridley and L. Oxburgh, editors. San Diego, Academic Press/Elsevier.
Gridley, T., and S. Kajimura. (2014) Lightening up a notch: Notch regulation of energy metabolism. Nature Med. 20, 811-812.
Murray, S.A., and T. Gridley. (2006) Snail family genes are required for left-right asymmetry determination but not for neural crest formation in mice. Proc. Natl. Acad. Sci. USA. 103, 10300-10304.
Zhang, N., and T. Gridley. (1998) Defects in somite development in lunatic fringe deficient mice. Nature 394, 374-377.
Gendron-Maguire, M., M. Mallo, M. Zhang and T. Gridley. (1993) Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest. Cell 75, 1317-1331.
Professor of Medicine, Tufts University School of Medicine