Research Interests
- Ischemic Stroke Care in the ED
- Hemorrhagic Stroke Care in the ED
- Cardiovascular and Immune Effects after Subarachnoid Hemorrhage
Dr. Madeleine Puissant is an attending Emergency Medicine physician at Maine Medical Center, Assistant Professor of Emergency Medicine at the Tufts University School of Medicine and Faculty Scientist I at the Center for Interdisciplinary Population & Health Research. She completed her PhD in neurophysiology at Medical College of Wisconsin, her medical degree at the University of Wisconsin School of Medicine and Public Health, and completed her residency at Maine Medical Center. Her clinical interests include streamling and improving timeliness of care to acute ischemic and hemorrhagic stroke patients in the emergency department. Additional focus includes studying the pathophysiologic processes underlying teh development cardiac and inflammatory complications after subarachnoid hemorrhage in order to develop novel therapeutic interventions. She is the PI on a pilot clinical trial of beta-blockers versus placebo in the acute phase of subarachoid hemorrhage (Beta-1 adrenergic inhibition to reduce catecholamine-induced cardiac injury and inflammation after subarachnoid hemorrhage (BADCATS)) and PI on an observational study looking at cardiac and inflammatory side effects after SAH in the neurointensive care unit (Cardiac dysfunction and inflammation after subarachnoid hemorrhage (BOBCATS)). Dr. Puissant is working on developing a murine model of SAH to augment clincial studies.
