COBRE in Mesenchymal & Neural
Regulation of Metabolic Networks
Building research excellence in understanding causes of metabolic disease
M-COBRE News, Timeline & Photos
Timeline
Pilot Project Award
Principal Investigator: Dr. Larisa Ryhzova
Title: Comparison of Cas9 mRNA Versus Cas9 Protein for Effective Genome Modification in the Mouse
Proteomics & Lipidomics Core Addition
The Proteomics and Lipidomics Core facility welcomed new hire, Kieran Wynne.
Pilot Project Award
Principal Investigator: Dr. Robert Friesel
Title: Cardiometabolic Syndrome in Spry1 Deficient Mice
Pilot Project Award
Principal Investigator: Dr. Robert Koza
Title: The Transcriptome for UCP1-Independent Thermogenesis
Seminar Presentation at External Advisory Board Retreat
Joseph Nadeau, PhD, Pacific Northwest Research Institute, Seattle, WA. Seminar Presentation: Mendel 2.0: Disease risk and unconventional modes of inheritance
Annual External Advisory Board Retreat
A successful end to the Metabolic COBRE Annual External Advisory Board Retreat.
Annual External Advisory Board Retreat
The Metabolic COBRE Annual External Advisory Board Retreat was held July 31- Aug. 1, in Portland, Maine.
7th Biennial National IDeA Symposium of Biomedical Research Excellence
Highlights from the 7th Biennial National IDeA Symposium held June 24-26 in Washington, DC. Left: Dr. Calvin Vary at poster, “A novel lipidomic approach to understand human diabetic heart disease”, Dr. Ilka Pinz, Dr. Michael Robich, Dr. Sergey Ryzhov, Dr. Douglas Sawyer, and Dr. Calvin Vary. Right: Dr. Julie Dragon (UVM), Dr. Cliff Rosen (MHIR) and Dr. Tom Gridley (MHIR) at Symposium
Cardiometabolic Young Investigators Forum
This event was a unique opportunity for young investigators to engage with thought leaders in clinical and translational research in a forum setting. Featured guests included: Dr. Sven Enerbäck, MD, PhD, Dr. Ron Margolis, PhD, NIDDK, Dr. Karen Freund MD MPH, and Dr, Clifford Rosen, MD, Center for Clinical & Translational Research at MHIR. The event was sponsored by the Metabolic Networks COBRE, Northern New England Clinical & Translational Research Network, and MaineHealth Institute for Research.
Clinical Partners/Researchers’ Monthly Meeting
Dr. Brian McGrory was the featured speaker at a roundtable discussion with MHIR basic scientists about the variation in bone quality he sees in his patients, the behavior of bone and joints in patients with certain diseases (e.g. diabetes, obesity, vascular disease), and the challenges he experiences in doing orthopedic surgery on varying patients.
Clinical Partners/Researchers’ Monthly Meeting
Dr. Michael Robich and Dr. Jeffrey Rosenblatt were the featured speakers at a roundtable discussion with MHIR basic scientists about their clinical experience with cardiovascular disease.
Year 1 Pilot Project Award
Principal Investigator: Dr. Volkhard Lindner
Title: Increase of metabolic efficiency by CTHRC1
Clinical Partners/Researchers’ Monthly Meeting
Dr. Kirk Sahagian, DO, FACS, Maine Medical Partners Surgical Care Casco Bay was the featured speaker for the monthly M-COBRE meeting. Dr. Sahagian’s visit featured a roundtable discussion with basic scientists about how his and his colleagues’ work in their integrated weight and wellness center can complement the research at MHIR.
Clinical Partners/Researchers’ Monthly Meeting
Featured guest, Dr. Irwin Brodsky, discussed the unresolved clinical problems of type 2 diabetes with lipodystrophic features; hitting upon both patients with diabetes who are metabolically unhealthy and non-obese, as well as those who are metabolically healthy obese.
Dr. Reagan Featured in Special Issue
In the February special issue of ACS Biomaterials Science & Engineering, Dr. Michaela Reagan was the Co-Editor for the issue and had an article on Tissue Engineering.
Dr. Brown Presenting at SMMC
Dr. Aaron Brown will be presenting at Southern Maine Community College (SMCC) during their Science Department Seminar. Topic:
Brown Adipose-based Therapies to Combat Obesity and Diabetes
Update Dr. Volkhard Lindner’s Lab
Work shows osteocytes in cortical bone expressing CTHRC1
Clinical Partners/Researchers’ Monthly Meeting
Featured guest, Dr. Michael Dedekian, Pediatric Endocrinology, shared his experience with childhood obesity.
Clinical Partners & Researchers’ Collaborative Meeting
Guest Presenter: Eric Dinnerstein, MD, Maine Medical Partners, Neurology
Reagan Lab Attends the ASH Conference
Carolyne Falank, PhD; Michaela Reagan, PhD; and Heather Fairfield, MS present poster at the American Society of Hematology.
