COBRE in Mesenchymal & Neural
Regulation of Metabolic Networks

Building research excellence in understanding causes of metabolic disease

M-COBRE News, Timeline & Photos

Timeline

2018
September 22

Pilot Project Award

Principal Investigator:  Dr. Larisa Ryhzova

Title:  Comparison of Cas9 mRNA Versus Cas9 Protein for Effective Genome Modification in the Mouse

 

September 15

Proteomics & Lipidomics Core Addition

Proteomics & Lipidomics Core Addition

The Proteomics and Lipidomics Core facility welcomed new hire, Kieran Wynne.

September 12

Pilot Project Award

Principal Investigator:  Dr. Robert Friesel

Title:  Cardiometabolic Syndrome in Spry1 Deficient Mice

 

August 15

Pilot Project Award

Principal Investigator:  Dr. Robert Koza

Title: The Transcriptome for UCP1-Independent Thermogenesis

 

August 1

Seminar Presentation at External Advisory Board Retreat

Seminar Presentation at External Advisory Board Retreat

Joseph Nadeau, PhD, Pacific Northwest Research Institute, Seattle, WA. Seminar Presentation:  Mendel 2.0: Disease risk and unconventional modes of inheritance

 

August 1

Annual External Advisory Board Retreat

Annual External Advisory Board Retreat

A successful end to the Metabolic COBRE Annual External Advisory Board Retreat.

 

July 31

Annual External Advisory Board Retreat

Annual External Advisory Board Retreat

The Metabolic COBRE Annual External Advisory Board Retreat was held July 31- Aug. 1, in Portland, Maine.

 

June 24

7th Biennial National IDeA Symposium of Biomedical Research Excellence

7th Biennial National IDeA Symposium of Biomedical Research Excellence

Highlights from the 7th Biennial National IDeA Symposium held June 24-26 in Washington, DC. Left: Dr. Calvin Vary at poster, “A novel lipidomic approach to understand human diabetic heart disease”, Dr. Ilka Pinz, Dr. Michael Robich, Dr. Sergey Ryzhov, Dr. Douglas Sawyer, and Dr. Calvin Vary.   Right: Dr. Julie Dragon (UVM), Dr. Cliff Rosen (MHIR) and Dr. Tom Gridley (MHIR) at Symposium

 

June 22

Cardiometabolic Young Investigators Forum

Cardiometabolic Young Investigators Forum

This event was a unique opportunity for young investigators to engage with thought leaders in clinical and translational research in a forum setting. Featured guests included: Dr. Sven Enerbäck, MD, PhD, Dr. Ron Margolis, PhD, NIDDK, Dr. Karen Freund MD MPH, and Dr, Clifford Rosen, MD, Center for Clinical & Translational Research at MHIR.   The event was sponsored by the Metabolic Networks COBRE, Northern New England Clinical & Translational Research Network, and MaineHealth Institute for Research.

 

June 6

Clinical Partners/Researchers’ Monthly Meeting

Dr. Brian McGrory was the featured speaker at a roundtable discussion with MHIR basic scientists about the variation in bone quality he sees in his patients, the behavior of bone and joints in patients with certain diseases (e.g. diabetes, obesity, vascular disease), and the challenges he experiences in doing orthopedic surgery on varying patients.

 

May 9

Clinical Partners/Researchers’ Monthly Meeting

Dr. Michael Robich and Dr. Jeffrey Rosenblatt were the featured speakers at a roundtable discussion with MHIR basic scientists about their clinical experience with cardiovascular disease.

May 1

Year 1 Pilot Project Award

Principal Investigator:  Dr. Volkhard Lindner

Title:  Increase of metabolic efficiency by CTHRC1

 

March 29

Clinical Partners/Researchers’ Monthly Meeting

Clinical Partners/Researchers’ Monthly Meeting

Dr. Kirk Sahagian, DO, FACS, Maine Medical Partners Surgical Care Casco Bay was the featured speaker for the monthly M-COBRE meeting. Dr. Sahagian’s visit featured a roundtable discussion with basic scientists about how his and his colleagues’ work in their integrated weight and wellness center can complement the research at MHIR.

February 14

Clinical Partners/Researchers’ Monthly Meeting

Clinical Partners/Researchers’ Monthly Meeting

Featured guest, Dr. Irwin Brodsky, discussed the unresolved clinical problems of type 2 diabetes with lipodystrophic features; hitting upon both patients with diabetes who are metabolically unhealthy and non-obese, as well as those who are metabolically healthy obese.

February 1

Dr. Reagan Featured in Special Issue

Dr. Reagan Featured in Special Issue

In the February special issue of ACS Biomaterials Science & Engineering, Dr. Michaela Reagan was the Co-Editor for the issue and had an article on Tissue Engineering.

January 29

Dr. Brown Presenting at SMMC

Dr. Aaron Brown will be presenting at Southern Maine Community College (SMCC) during their Science Department Seminar. Topic:

Brown Adipose-based Therapies to Combat Obesity and Diabetes

January 19

Update Dr. Volkhard Lindner’s Lab

Update Dr. Volkhard Lindner’s Lab

Work shows osteocytes in cortical bone expressing CTHRC1

January 10

Clinical Partners/Researchers’ Monthly Meeting

Clinical Partners/Researchers’ Monthly Meeting

Featured guest, Dr. Michael Dedekian, Pediatric Endocrinology, shared his experience with childhood obesity.

2017
December 14

Clinical Partners & Researchers’ Collaborative Meeting

Guest Presenter:  Eric Dinnerstein, MD, Maine Medical Partners, Neurology

December 9

Reagan Lab Attends the ASH Conference

Reagan Lab Attends the ASH Conference

Carolyne Falank, PhD; Michaela Reagan, PhD; and Heather Fairfield, MS present poster at the American Society of Hematology.