COBRE in Mesenchymal & Neural
Regulation of Metabolic Networks

Building research excellence in understanding causes of metabolic disease

M-COBRE News, Timeline & Photos

Timeline

2019
December 18

Clinical Partners/Researchers’ Monthly Meeting

Clinical Partners/Researchers’ Monthly Meeting

The monthly meeting featured Dr. Kinna Thakarar, DO, MPH, Infectious Disease, MaineHealth Institute for Research and Dr. Katy Garrett, PharmD, HIV/HCV Clinical Pharmacist at Maine Medical Center.

Drs. Thakarar and Garrett were hosted by Dr. Irwin Brodsky, Clinical Advisor to the COBRE project. They led a clinical-translational roundtable discussion about their clinical interests with participants, and reviewed descriptions of the lipodystrophy that comes with HIV disease and use of HIV medications.

December 16

Congratulations

Congratulations

Dr. Anyonya Guntur was appointed to Assistant Professor, Department of Medicine, Tufts University School of Medicine, Boston, MA

December 6

New COBRE Project & Project Leader Announced

New COBRE Project & Project Leader Announced

Congratulations to Principal Investigator Dr. Anyonya Guntur. His COBRE Project work is entitled:  “The essential role for mitophagy in osteoblast differentiation.”

October 23

Clinical Partners/Researchers’ Monthly Meeting

Clinical Partners/Researchers’ Monthly Meeting

The monthly meeting featured Dr. Johnson Liu.   Dr. Liu lead a clinical-translational round table discussion on general hematology (anemia, thrombocytopenia, disorders of coagulation), bone marrow failure syndromes, myelodysplastic syndromes, acute and chronic leukemia, and multiple myeloma.

October 16

Welcome

Welcome

Dr. Joe Nadeau joins MaineHealth Institute for Research as a Faculty Scientist III in the Center for Molecular Medicine. Dr. Nadeau will also be the Chairperson for the Metabolic COBRE Steering Committee.

October 11

Pilot Project Award

Principal Investigator:  Dr. Robert Friesel

 

Title:  Spry1 regulation of PDGFR-induced adipose tissue fibrosis

October 11

Pilot Project Award

Principal Investigator:  Dr. Kimberly Malka

 

Title:  Characterization of the Microenvironment Involved in Aortic Pathologies

October 11

Pilot Project Award

Principal Investigator:  Dr. Igor Prudovsky

 

Title:  CTHRC1 anti-adipogenic signaling

September 5

Clinical Partners/Researchers’ Monthly Meeting

The monthly meeting featured Drs. Esther Shao and Suni Malhotra. There was discussion on some of the clinical problems faced by patients with complex congenital heart disease.

 

July 30

Annual External Advisory Board Retreat

Annual External Advisory Board Retreat

COBRE Annual Retreat, July 30-31, External Advisory Board Left to right: Pamela Duncan, Evan Rosen, Tom Clemens, Cliff Rosen, Gerard Karsenty, Lucy Liaw.

 

May 2

Clinical Partners/Researchers’ Monthly Meeting

Clinical Partners/Researchers’ Monthly Meeting

Dr. Kilby discussed fatty liver/steatohepatitis, its clinical significance, and where the field of gastroenterology is going with regard to its diagnosis and management.

 

February 6

Clinical Partners/Researchers’ Monthly Meeting

Clinical Partners/Researchers’ Monthly Meeting

Dr. Michael Pinette, Maternal-Fetal Medicine, MaineHealth, led a round table discussion on fetal development.

January 30

Clinical Partners/Researchers’ Monthly Meeting

Clinical Partners/Researchers’ Monthly Meeting

Dr. Jeffery Rosenblatt presented on Cardiac Molecular Imaging

January 28

Outreach

Outreach

Dr. Michaela Reagan, was at Capitol Hill with fellow American Society for Bone & Mineral Research (ASBMR) members advocating for NIH funding and bills that support bone health.

January 15

Publication

Dr. Cal Vary’s research was published in Molecular Cancer Research:  Interactions with Muscle Cells Boost Fusion, Stemness, and Drug Resistance of Prostate Cancer Cells

January 4

Publications

Dr. Michaela Reagan’s research was published in Frontiers In Endocrinology:  Interleukin-6 Interweaves the Bone Marrow Microenvironment, Bone Loss, and Multiple Myeloma and JBMRPlus:  Multiple Myeloma and Fatty Acid Metabolism

 

 

 

2018
December 12

Clinical Partners/Researchers’ Monthly Meeting

Clinical Partners/Researchers’ Monthly Meeting

 Dr. John Vella, MaineHealth, Nephrology. Dr. Vella visited to generate a discussion on the effects of kidney disease (early dysfunction to uremia) on metabolism and to engage in a conversation describing patients with kidney disease through the eyes of the clinician and sharing what gaps in knowledge in Nephrology provide the greatest vexation for the Nephrologist.

December 11

Publication

Publication

Dr. Aaron Brown’s research was published in Cell Reports:  A Renewable Source of Human Beige Adipocytes for Development of Therapies to Treat Metabolic Syndrome

December 8

Pilot Project Award

Principal Investigator:  Dr. Ilka Pinz & Dr. Doug Sawyer

Title:  A Comparison of Cardiac Lipid Composition in CABG Patients on Mediterranean vs. Standard diet

November 28

Clinical Partners/Researchers’ Monthly Meeting

Clinical Partners/Researchers’ Monthly Meeting

Dr. Sarah Hallen, Geriatric Medicine, MaineHealth. Dr. Hallen visited to generate a discussion with researchers about The Frailty Phenotype: Clinical Implications of Homeostenosis.  Participants also engaged with her around the tissue changes that occur with aging and their implications for clinical frailty, the effect of aging on the brain, blood-brain barrier permeability and their clinical effects.