M-COBRE News, Timeline & Photos
Timeline
Clinical Partners/Researchers’ Monthly Meeting
The monthly meeting featured Dr. Kinna Thakarar, DO, MPH, Infectious Disease, MaineHealth Institute for Research and Dr. Katy Garrett, PharmD, HIV/HCV Clinical Pharmacist at Maine Medical Center.
Drs. Thakarar and Garrett were hosted by Dr. Irwin Brodsky, Clinical Advisor to the COBRE project. They led a clinical-translational roundtable discussion about their clinical interests with participants, and reviewed descriptions of the lipodystrophy that comes with HIV disease and use of HIV medications.
Clinical Partners/Researchers’ Monthly Meeting
The monthly meeting featured Dr. Johnson Liu. Dr. Liu lead a clinical-translational round table discussion on general hematology (anemia, thrombocytopenia, disorders of coagulation), bone marrow failure syndromes, myelodysplastic syndromes, acute and chronic leukemia, and multiple myeloma.
Pilot Project Award
Principal Investigator: Dr. Robert Friesel
Title: Spry1 regulation of PDGFR-induced adipose tissue fibrosis
Pilot Project Award
Principal Investigator: Dr. Kimberly Malka
Title: Characterization of the Microenvironment Involved in Aortic Pathologies
Pilot Project Award
Principal Investigator: Dr. Igor Prudovsky
Title: CTHRC1 anti-adipogenic signaling
Clinical Partners/Researchers’ Monthly Meeting
The monthly meeting featured Drs. Esther Shao and Suni Malhotra. There was discussion on some of the clinical problems faced by patients with complex congenital heart disease.
Publication
Dr. Cal Vary’s research was published in Molecular Cancer Research: Interactions with Muscle Cells Boost Fusion, Stemness, and Drug Resistance of Prostate Cancer Cells
Publications
Dr. Michaela Reagan’s research was published in Frontiers In Endocrinology: Interleukin-6 Interweaves the Bone Marrow Microenvironment, Bone Loss, and Multiple Myeloma and JBMRPlus: Multiple Myeloma and Fatty Acid Metabolism
Clinical Partners/Researchers’ Monthly Meeting
Dr. John Vella, MaineHealth, Nephrology. Dr. Vella visited to generate a discussion on the effects of kidney disease (early dysfunction to uremia) on metabolism and to engage in a conversation describing patients with kidney disease through the eyes of the clinician and sharing what gaps in knowledge in Nephrology provide the greatest vexation for the Nephrologist.
Pilot Project Award
Principal Investigator: Dr. Ilka Pinz & Dr. Doug Sawyer
Title: A Comparison of Cardiac Lipid Composition in CABG Patients on Mediterranean vs. Standard diet
Clinical Partners/Researchers’ Monthly Meeting
Dr. Sarah Hallen, Geriatric Medicine, MaineHealth. Dr. Hallen visited to generate a discussion with researchers about The Frailty Phenotype: Clinical Implications of Homeostenosis. Participants also engaged with her around the tissue changes that occur with aging and their implications for clinical frailty, the effect of aging on the brain, blood-brain barrier permeability and their clinical effects.