Research Interests
- Pediatric environmental health
- Pediatric endocrinology
Abby Fleisch, MD, MPH, is an environmental health researcher at MaineHealth Institute for Research, practicing pediatric endocrinologist at MaineHealth, Associate Professor of Pediatrics at Tufts University School of Medicine, and Adjunct Associate Professor of Environmental Health at Harvard School of Public Health. Dr. Fleisch completed residency in pediatrics at Boston Children’s Hospital/Boston Medical Center and a fellowship in endocrinology at Boston Children’s Hospital. She completed the Harvard-wide pediatric health services research fellowship and received a Master of Public Health from Harvard TH Chan School of Public Health.
Dr. Fleisch’s research is focused on the extent to which exposure to environmental toxicants prenatally and across the lifespan impact cardiometabolic and musculoskeletal health. Her work has demonstrated an impact of environmental chemicals including perfluoroalkyl substances (PFAS) on obesity and osteoporosis risk. Her studies include careful attention to vulnerable exposure windows, dietary confounding, potential mitigating effects of diet/lifestyle, and the health impact of multi-chemical exposure.
Dr. Fleisch leads a National Institute of Environmental Health Sciences (NIEHS) Outstanding New Environmental Scientist R01 award focused on PFAS and phthalate exposure, adiposity, and bone accrual across adolescence in the Project Viva cohort. She co-leads an R01 award from NIEHS and a U01 award from the National Institute on Aging, each focused on the impact of PFAS on chronic health outcomes (e.g., musculoskeletal health and cardiovascular disease) within the Diabetes Prevention Program. Dr. Fleisch also co-leads an NIEHS R21 award to examine exposure pathways and mental health impacts of PFAS-contaminated biosolids used as fertilizer in central Maine. Dr. Fleisch has been honored through research awards at the Society for Pediatric Research (featured member), Endocrine Society (early career investigator award), and NIEHS (story of success).
Complete list of published work in MyNCBI Bibliography: My Bibliography – NCBI (nih.gov)
Lin PD, Cardenas A, Rokoff LB, Rifas-Shiman SL, Zhang M, Botelho J, Calafat AM, Gold DR, Zota AR, James-Todd T, Hauser R, Webster TF, Oken E, Fleisch AF. Associations of PFAS concentrations during pregnancy and midlife with bone health in midlife: Cross-sectional and prospective findings from Project Viva. Environ Int. 2024 Dec;194:109177. PubMed Central PMCID: PMC11683763.
Rokoff LB, Rifas-Shiman SL, Aris IM, Lin PD, Rosen CJ, Calafat AM, Gordon CM, Oken E, Fleisch AF. Mid-Childhood Plasma Concentrations of Per- and Polyfluoroalkyl Substances, Modifiable Lifestyle Factors, and Bone Mineral Density Through Late Adolescence. Environ Sci Technol. 2024 Nov 12; 58(45):19970-19980. PubMed Central PMCID: PMC11562948.
Criswell R, Fleisch AF, Ducatman A. Clinical Implications of New Drinking Water Regulation for “Forever Chemicals”. JAMA. 2024 Sept 10; 332 (10):785-786. PubMed Central PMCID: PMC11574710.
Seshasayee SM, Rifas-Shiman SL, Chavarro JE, Carwile JL, Lin PD, Calafat AM, Sagiv SK, Oken E, Fleisch AF. Dietary Patterns and PFAS Plasma Concentrations in Childhood: Project Viva, USA. Environment International; 2021. 151:106415. PMID: 33706127.
Janis JA, Rifas-Shiman SL, Seshasayee SM, Sagiv S, Calafat AM, Gold DR, Coull BA, Rosen CJ, Oken E, Fleisch AF. Plasma Concentrations of Per- and Polyfluoroalkyl Substances and Body Composition From Mid-Childhood to Early Adolescence. J Clin Endocrinol Metab. 2021 Aug 18;106(9):e3760-e3770. PubMed Central PMCID: PMC8372642.