Matthew S. Siegel, MD

Director, Autism & Developmental Disorders Inpatient Research Collaborative (ADDIRC)

Faculty Scientist

 Research Interests

  • Developmental disorders
  • Childhood autism
Dr. Siegel is the Director of the Developmental Disorders Program of Spring Harbor Hospital and is actively researching and publishing in the area of autism and serious behavioral disturbance. He attended Amherst College and Stanford Medical School and completed Triple Board Training at Brown University in child psychiatry, psychiatry and pediatrics.

He is a Clinical Investigator at the MaineHealth Institute for Research, an assistant professor in the Department of Psychiatry of Tufts University School of Medicine, and the founder of a national inpatient research collaborative on children with autism and developmental disorders.

Dr. Siegel serves on the Autism and Intellectual Disability Committee of the American Academy of Child and Adolescent Psychiatry. He is the PI for a multi-site phenotype-genotype study of children severely affected by autism that will examine relationships between phenotypic domains of communication, intelligence, psychiatric co-morbidity and corresponding genetic pathways.

Goodwin MS, Mazefsky CA, Ioannidis S, Erdogmus D, and Siegel M. Predicting aggression to others in youth with autism using a wearable biosensor. Autism Res. 2019 Aug;12(8):1286-1296. doi: 10.1002/aur.2151.

Stedman A, Taylor BJ, Erard M, Peura C and Siegel M. Are Children Severely Affected by Autism Spectrum Disorder Underrepresented in Treatment Studies? An Analysis of the Literature, Journal of Autism and Developmental Disorders 2018 Dec 10.

Siegel M. The Severe End of the Spectrum: Insights and Opportunities from the Autism Inpatient Collection (AIC). J Autism Dev Disord. 2018 Nov;48(11):3641-3646. doi: 10.1007/s10803-018-3731-6.

Taylor BJ, Sanders KB, Pedersen KA…and Siegel M, Inpatient Psychiatric Treatment of Serious Behavioral Problems in Children with Autism Spectrum Disorder (ASD): Specialized Versus General Inpatient Units. J Autism Dev Disord. 2018 Nov 21.

Kuriakose S, Filton B, Marr M…Siegel M, Horowitz, S, and Havens J, Does an Autism Spectrum Disorder care pathway improve care for children and adolescents with ASD in inpatient psychiatric units? J Autism Dev Disord. 2018 July 3. Doi: 10.1007/s10803-018-3666-y.

McGuire K and Siegel M, Psychiatric hospital treatment of youth with autism spectrum disorder in the United States: needs, outcomes, and policy. Int Rev Psychiatry. 2018 Feb;30(1):110-115. doi: 10.1080/09540261.2018.1433134. Epub 2018 Mar 14.

Mazefsky CA, Yu L, White SW, Siegel M, Pilkonis PA. The Emotion Dysregulation Inventory: Psychometric properties and item response theory calibration in an Autism Spectrum Disorder Sample. Autism Research 2018, 11: 928-941.[Article]

Handen BL, Mazefsky CA, Gabriels RL, Pedersen KA, Wallace M, Siegel M.  Risk factors for self-injurious behavior in an inpatient psychiatric sample of children with Autism Spectrum Disorder.  J Aut Devel Disord. 2018 Jan 24.[Article]